In the first episode of a two-part "Castle" event, Castle and Beckett pursue a ruthless killer who, they discover, is part of a sinister, international conspiracy. Castle and Beckett are joined on the case by Sophia Conrad, a smart, sexy CIA operative who has a complicated past with Castle. Josh Stamberg, also guest stars as Martin Danberg, an intelligence officer.

When a woman dressed as Red Riding Hood is found dead in the woods with claw marks covering her body, and soon after a murdered Snow White is discovered with a poison apple in her hand, Castle & Beckett find themselves on a Grimm hunt to catch a fairytale killer before he kills again. But nothing is as it seems in a case filled with deceit, betrayal, secrets and murder.