The murder of a high school mean girl draws Castle back to one of his many alma maters, where he is giddy to learn that the evidence points to a surprising perpetrator - a teenage telekinetic, throwing he and Beckett into a real-life "Carrie".

Beckett is recruited to assist on a Narcotics investigation, but a routine mission turns deadly when an undercover operation goes array. To survive, Beckett must engage in a battle of wits against some of the most dangerous men in the New York underworld—including a powerful enemy from her past.