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Mindy's fertility practice is in danger and Annette's upcoming surgery looms large. While Mindy and Danny wait for word on the surgery, Mindy attends Morgan and Tamra's dream wedding, where she and the rest of the Shulman gang try to find their own happy endings.
Mindy and Danny can't agree on the best way to care for an ailing Annette. Meanwhile, Anna throws a disastrous bridal/baby shower for Tamra, where Colette has a heated confrontation with her brother, Jody.
Annette (Rhea Perlman) is furious when Mindy uncovers a secret about her and decides to get involved. Jody attempts to keep his new girlfriend (Ana Ortiz) from taking a job overseas, while Tamra dives head- first into Morgan's religion.
Mindy is forced to go solo on the honeymoon that Ben had planned for them. Hoping for relaxation and a new romance, Mindy instead finds herself on a vegan wellness retreat with her ex-fiancé Casey (Anders Holm) and his hot new wife.
Shulman and Associates is turned upside down when Mindy hires a down-on-his-luck Brendan Deslaurier (Mark Duplass). Meanwhile, rumors fly about who's the father of Tamra's baby.
Jeremy's hosting a party the office is actually excited for! Adding to the intrigue, Mindy invites a handsome stranger (Yassir Lester) who has an unexpected interest in Shulman and Associates. Jody competes with a beautiful doctor (Ana Ortiz) after she steals one of his patients.
Mindy goes toe to toe with a cliquey mom at Leo's school. Meanwhile, Tamra fends off the advances of an ex she never thought she'd backslide with.
Mindy turns to her ex Cliff (Glenn Howerton) for help navigating her messy divorce. But Peter (Adam Pally) is back in town to help pull Mindy out of her slump with an epic office karaoke party!
Mindy and Ben's relationship is put to the test when Ben gets an interview for a job in Philadelphia. Meanwhile, Anna gets the girls of the office together for an ill-fated girls' night where Tamra realizes she might have feelings for a co-worker.
Shulman & Associates is buzzing with drama! As Mindy adjusts to married life with Ben, Jeremy tries to take things to the next level with Anna, while Tamra makes a life-changing decision.