Mindy decides to cook Thanksgiving dinner at Gwen's house, but she is completely caught off guard when her former blind date, Dennis, arrives with his new girlfriend. Meanwhile, a lonely Danny mans the empty office while Betsy and Jeremy visit Betsy's eccentric family for the holiday.

Mindy isn't getting respect from Danny and Jeremy, so she goes off to experience life as her own boss. Meanwhile, the group fights back when they discover that holistic midwives are stealing patients from Shulman & Associates.