Mindy has made up her mind to move to San Francisco and start a practice with Rob, but her credit history jeopardizes their ability to get a loan. Meanwhile, Danny tries to let the office know that he is moving to San Francisco with Mindy, but they're convinced his "big news" is something completely different.

Mindy's fertility clinic opens, but with zero track record in the fertility field, attracting new patients is tougher than she imagined. Meanwhile, at Shulman & Associates, the nurses try to raise money for obese nurses while trying to get to know Dr. Bergdahl.