A nurses' strike spearheaded by a new male nurse shakes Shulman & Associates to its core. Meanwhile, Mindy cares for a sick Leo; Jody puts the upstairs apartment on the market; and Brendan asks Mindy for help with a new project.

The practice needs a doctor until Jeremy is back on his feet following his heart attack, but Mindy has reservations about the new ob-gyn's gender. Meanwhile, Ben's living situation could be a deal breaker for Mindy.