Hotchner and the BAU team fear they are facing a mission-based serial killer, or multiple killers, when a 911 phone call quoting bible passages from Revelations is placed by someone in the house just seconds before the murders occur. As the team begins their profile, Garcia discovers that the tech-savvy unsub sent out a video of the murders over the Internet just hours after they were committed, which is viewed by millions of users. Meanwhile, Hotchner, Morgan and Prentiss must determine how many people are actually responsible for the murders since different voices can be heard on the 911 recording and on the video.

The BAU team travels to an upscale New York neighborhood to hunt a serial killer they fear is racially motivated.