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After a series of suspicious murders occur, Prentiss suspects her old Interpol nemesis, making her fear for the safety of her BAU team as he closes in on her.
Reid makes a connection with an autistic child that could assist the BAU in finding the boy's missing parents. Also, Prentiss enlists two former Interpol colleagues in hunting an old nemesis.
Prentiss is ready to confront her nemesis, Ian Doyle, once and for all. Meanwhile, the BAU calls upon JJ to help them find Prentiss and capture Doyle before it's too late.