When the bodies of two seemingly unrelated victims are found just hours apart in San Diego and Los Angeles respectively, the BAU suspects that that not one, but two killers are working together to commit these murders.

When a legless body is found in the New Mexico desert and a second unwilling amputee shows up at the hospital, the BAU team searches for this amateur surgeon before he preys upon his next reluctant victim. Also, Reid's phone calls to a mystery woman have the team intrigued.