Jane Galloway is a nervous breakdown waiting to happen. She has completely shielded herself from the outside world, but that doesn't stop a stalker in her attic from killing her. When CSI arrives, they find her hair dyed and her face shoved in the toilet. This image has a heavy impact on Nick, and they soon realize that this stalker is well acquainted with Nick, which makes the CSI the next target.

Grissom and Sara investigate when a man's body, which has been doused with lye, is found buried in a park; Nick tries to determine how a hiker apparently drowned in a desert.