Grissom and Catherine investigate the murder of a wealthy couple who are found outside of their home, which was up for sale. Meanwhile, Sara probes the death of a cheerleader who is found eviscerated on a soccer field, her organs having been ingested by her killer.

Grissom, Warrick, and Sara investigate when a woman vanishes while taking part in a magician's act. The primary suspect is the magician. Catherine and Nick investigate the apparent overdose of a rock star.