Warrick and Grissom investigate the death of a man found at a foam party. Nick works on the case of a man found dead in his home. Catherine and Grissom investigate the death of a women who was involved with the aforementioned two men, all of which lead to Lady Heather. Catherine desperately tries to find out where her missing daughter and ex-husband are. Sara eventually takes over the case.

An elderly woman crashes her car into a crowded restaurant. One of the patrons is Sara's paramedic boyfriend. Grissom and Nick investigate the possible carbon monoxide murder of a woman in her home.