Grissom, Warrick, and Sara investigate when a woman vanishes while taking part in a magician's act. The primary suspect is the magician. Catherine and Nick investigate the apparent overdose of a rock star.

A boxing champ dies in the ring after taking a brutal beating from his nemesis, but Grissom finds evidence that points to murder. Outside, in a nearby parking lot, Catherine works a crime scene where a Los Angeles gang member was gunned down, apparently by a rival gang. Also, Nick investigates a jewelry-store robbery.