A robbery at a grocery store results in a shootout leaving five dead. The police officer at the scene believes Grissom has a grudge against him. The entire team has to process the enormous amount of evidence at the scene.

Catherine and Sara deal with the death of what at first seems to be a transvestite. Later during autopsy they find out that the make-up he seemed to be wearing was actually facepaint, he was a clown. Grissom, Nick, and Warrick deal with the death of a man in a homeless area. They found out he worked in a recovery center for drug users.