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Roni convinces Weaver to check on Lucy's story of Regina Mills adopting a baby boy in Boston. Meanwhile, Rogers turns to Tilly for help with Eloise's disappearance, and in the past Regina teaches Drizella how to do magic.
Sabine convinces Jacinda to join her in a baginet-making operation so that they can escape Victoria's tyranny, but Victoria has a plan of her own. In the past, Tiana sets out to find a prince with the help of a traveling soothsayer, Dr. Facilier, but Facilier has a plan to get the Firefly Ruby in Tiana's possession.
Rogers gets a lead on Eloise's location, but is unaware that he's being played to release someone more powerful than he knows. In the past, Hook climbs a tower to rescue the long-haired beauty within and obtain a magical flower that he needs to get his revenge.
After six seasons, the residents of the enchanted forest face their greatest challenge yet as The Evil Queen, Captain Hook and Rumplestiltskin join forces with a grown up Henry Mills and his daughter Lucy on an epic quest to once again bring hope to their world and ours. Along the way, new fairy tale characters and old search for true love, find adventure and once again take sides in the struggle of good against evil, as classic tales are once more twisted and reimagined.