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While investogating the murder of an English tutor who stole a valuable artifact from a British museum, Patrick Jane, Lisbon, and the CBI team brace themselves to finally meet their new boss, Madeleine Hightower.
When Dr. Alicia Seberg, a government research scientist, is exposed to a deadly toxin while at work and has only hours to live, she calls Patrick Jane and the CBI to find her murderer.
When a Jane Doe with amnesia and covered in blood steps in front of Cho and Van Pelt's car, Patrick Jane must use all of his skills to discover who she is, her last location, and why she lost her memory.