Jane Villanueva is a driven young woman studying to become a teacher, nursing a dream to be a writer, and supporting herself with a job at a hot new Miami hotel. All the years of watching telenovelas with the two women who raised her - her sexy, young-at-heart mother, Xiomara and her still-devout grandmother, Alba - have given Jane a slightly unrealistic view of romance, but her wonderful fiancé, Michael, is supportive and even understands her decision to "save herself" until marriage. All of Jane's meticulous life plans are turned upside down, however, when she sees her doctor for a routine check-up and is accidentally artificially inseminated with a specimen meant for someone else. Now, Jane is faced with the most important decisions of her life - a life that has suddenly become as dramatic, complicated and unpredictable as the telenovelas she has always loved.

Jane considers making a life-changing decision about her and Michael's relationship. Alba is disappointed in Xo's handling of Rogelio, so Alba takes it into her own hands to stop Rogelio from trying to see Jane. Meanwhile, Jane continues to question whether Petra will be a fit mother, and her pursuit of the truth leads to an unexpected change in their relationship. Michael's on-going murder investigation leads to an unexpected discovery.