Sherlock investigates a case involving a wealthy philanthropist who believes his incurable illness was given to him on purpose. Meanwhile, Sherlock tries to teach Joan his deductive skills by sending her to a suspicious dry cleaning establishment.

Sherlock and Joan try to prevent a robbery from one of the largest cash vaults in the country during the middle of a Nor'easter. Meanwhile, Sherlock tries to help a transgender woman who is recovering from her latest break-up.