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Holmes and Watson search for an ulterior motive when Cassie Lenue, a brilliant young criminal they helped put in prison, seeks their help in solving a murder.
Holmes and Watson investigate the murder of a criminal who made his living by stealing from other criminals. Also, when Captain Gregson resumes leadership of the precinct, he suspects his interim replacement, Captain Dwyer, is responsible for one of his best detective's suspicious departure.
Holmes and Watson work to determine if a long dormant serial killer has resurfaced in the wake of a sculptor's murder in New York City. Also, Watson suspects Holmes is keeping something from her regarding tech billionaire Odin Reichenbach.
In season seven, Holmes and Watson's new careers as consultants for Scotland Yard are disrupted by news that a member of their inner circle has been gravely wounded in the United States. As Holmes' stateside legal trouble – the result of a confession to a murder he didn't commit – threatens to keep them from returning to New York, their greatest foe to date, tech billionaire Odin Reichenbach, waits on the horizon to test their limits.