The stagecoach in which Bat Masterson, Major Mars and pretty Lottie Tremaine are traveling is waylaid by a vengeful gang led by an Indian whose family was slain when the Major's men wiped out a village. Bat is forced to defend the Major.

Bat's lucrative contract to build a railroad in Colorado is in jeopardy. His crew is menaced by natural disasters and then wagon loads of equipment are lost. Just when things it seems things can't get worse, Bat is arrested for murder.