Jackie becomes determined to stop dealing and makes one last purge of her stash with Eddie, but the deal goes awry just as their relationship reaches a new level. Meanwhile, Zoey blames herself for a patient's death and Carrie steps forward as an unlikely ally; and Dr. Prince and Akalitus bond over lunch when she reveals something from her past.

Jackie and Zoey set out on an unexpected road trip. Stressed out by the long drive, Zoey finally confronts Jackie with her frustration. Meanwhile, Dr. Prince attracts a neighborhood mob to All Saints.