When Catherine's dad gets remarried, the bride-to-be and her bridesmaids try to find the daughter-of-the-groom a date for the wedding. Uncomfortable with being set up, Cat reluctantly admits that she's seeing somebody and confides to Vincent that she wishes he could be her date. At the wedding reception, Cat learns about a research grant that Evan received to study the mutant DNA cells found at local crime scenes. When she tells Vincent about Evan's theory of how the cells are changing to become more animal-like and less human, she encounters an unexpected detour that could change the course of their relationship. Meanwhile, Tess and Joe cross the line romantically despite the fact that Joe is a married man.

Vincent is torn between his new feelings for Cat and his old memories with Alex. J.T. learns that Evan is planning to propose a task force to catch the beast and must figure out how to stop him. Meanwhile, Tess investigates the mysterious skydiving death of the wife of a billionaire adventurer, while Cat remains off duty until she recovers from being shot.