Chuck and Sarah put aside spy work to have a weekend of debauchery, but Awesome's plans for Chuck's big night don't go quite as expected. Meanwhile, Ellie's investigation into her father's computer leads to a life changing discovery.

Before he can kiss the bride, Chuck must enlist his wedding party to take down Vivian Volkoff and stop her from destroying the big day. When he turns to Alexei Volkoff for help, the CIA sends its toughest agent, Clyde Decker, to stop them.