Callie and Brandon go on an unplanned trip to Mexico. Meanwhile, an empty pregnancy-test box is found in the house, and Stef and Lena wonder if someone may be pregnant.

Stef and Lena hesitate to give their blessing when Mariana's biological grandfather tells her she must be baptized in order to be her new half-sister Isabella's godmother. Callie's actions at her birthday party are called out by Stef, and they make a big decision in order to avoid jeopardizing her adoption.