In the premiere, "Pilot," Savannah ("Savi") is a successful career woman working toward the next phase in her life -- both professionally and personally -- bucking for partner at the law firm where she works while also trying to start a family with her husband, Harry. But when their fertility issues begin to take center stage, Savi finds herself attracted to her flirtatious colleague, Dominic. Savi's free-spirited and capricious baby sister, Josslyn, couldn't be more different, living single, serial dating and partying. A real estate agent, Josslyn has no interest in a committed, long-term relationship.

Tensions escalate at work between Savi and Dom; Joss's new boss, Olivier -- very French and very unimpressed with her -- gives her an impossible assignment; and Karen continues to be drawn into the dysfunctional Grey family orbit.