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Two of Alcatraz's most violent brothers, Herman and Pinky Ames, who were notorious for nearly escaping in 1963, find something mysteriously amiss when they return to Alcatraz in the present day.
Madsen and Hauser hunt down Johnny McKee a former Alcatraz inmate and vicious killer with a background in chemistry. It's a race against time before McKee horrifically poisons more innocent victims. Meanwhile, more details emerge about Madsen's grandfather.
Sonny Burnett a man with an incredible dark side who became ultra-violent during his stint at Alcatraz, returns .