Ellen must decide whether to save Duncan's life, and later decides to confront his wife. Meanwhile, Creasy meets with Vanessa and Colonel Blair after the President informs them that he wants to expose the details of Operation Total Information, a government surveillance program that allowed intelligence agencies to spy on U.S. citizens.

After a member of the President's staff is murdered, Ellen urges Duncan to back out of the assassination plot, while other members of the President's staff take matters into their own hands. Meanwhile, after scouring Nina's medical records, Ellen finds someone who might be a viable bone marrow donor.