Paramedic, Tina Spittle, and technician, Donna Parcell are called to a taxi that has flipped over after being hit from behind on the M6 motorway. Driver Ali managed to get out, but his two passengers are still stuck inside. Meanwhile, paramedics Gaz Clarke and Lee Timbrell help 25-year-old Emma who has suspected sepsis, which is one of the UK's biggest killers. And paramedics Ollie Raven and V Hodgkins treat 74-year-old John who has critically low blood pressure. John has a series of health problems, but he's had a sudden deterioration. Ollie and V call for backup to get him out of his house and to hospital.

A young man has a seizure and a police officer is involved in a car accident.