Dr. Lee Rosen and his team of Alphas, extraordinary individuals who can stretch the capabilities of the human mind, investigate an implausible murder at the behest of the Department of Defense.

The team of Alphas, including new member Hicks, relocates to new offices in Queens after the attack on Dr. Rosen's life. While adjusting to their new surroundings the team investigates a series of violent public riots that are breaking out on the east coast. The only connection between the riots is a runaway teen, an Alpha, who overproduces certain pheromones that causes people nearby to become violent. Rosen's team must find a way to stop this Alpha without losing control themselves.