An epic storm hits San Antonio and the emergency room is awash in patients and must use their battlefield skills to deal with massive power outages. TC and Dr. Scott Clemmens race to the scene of a mudslide disaster to treat a gravely injured mother and her son. Paul rises to the challenge of caring for the boy, whose condition takes an unexpected turn for the worse. Scott considers an offer from Ragosa to join the hospital staff as head trauma surgeon. Jordan isn't sure that's going to work out with the tensions between TC and Scott. Landry is caught by surprise when a family member shows up at the hospital looking for money to cover his debts. She finds some needed moral support from Ragosa. Meanwhile, Topher must head out into the storm to help his wife who is stranded and going into labor with twins.

When a small plane goes down near San Antonio, TC and Topher chopper out to the scene and retrieve the lone survivor. Back in the ER, they deal with his serious injuries but must fend off Milo, a menacing law enforcement officer with a hidden agenda. Paul is mesmerized by an injured exotic dancer who lands in the emergency room after falling during her performance. When her condition takes a mysterious turn for the worse, Paul, Kenny and Drew are baffled by her life threatening symptoms and must go to an already swamped Jordan for help. Krista tries to help a teenager with a serious eating disorder that her family refuses to recognize. Meanwhile, TC struggles with increasing flashbacks and the traumatic death of his brother in Afghanistan.