As they arrive in a new city, Ash & Co. quickly learn that Team Plasma are there and are using their technology to once again manipulate Pokémon. In doing so, the Pokémon Haxorus starts destroying the city. Iris protests at this, claiming there's no way a Dragon-type Pokémon can be bad. In trying to stop the rampage, Iris' Dragonite soon falls to Team Plasma's manipulation, and N can no longer hear the Pokémon's hearts. N is worried and tries to stop the Pokémon, but ends up becoming their next target. Will they be able to stop Team Plasma's plans?

Having infiltrated Team Plasma's hideout, Meowth confronts Colress and tries to convince him to switch sides to use his skills to work for Team Rocket. Colress, however, is insistent that he can awaken Meowth's true powers using his machines and attempts it, with Jessie & James watching from afar. However, as Meowth has specially trained his mind to prevent being put under control, things look bleak for Colress until the machine finally puts Meowth under control and starts attacking with its Fury Swipes until Colress has him turn on Jessie & James. Will they be able to snap Meowth out of it?