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Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.
After revealing a scientific mystery around Tramadol-addicted cows in West Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.
With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.