Prince, the pop superstar who sold over 100 million records over a 30 year career, was fit, health-conscious, and vehemently anti-drugs, and yet, on April 21, 2016, Prince died, shockingly, of a drug overdose; the case is still under investigation.

Best known for his roles in "Dirty Dancing'' and "Ghost,'' Patrick Swayze was a legendary actor, dancer and singer but he died at 57 years old in 2009 from cancer.