Hosted by Jane Pauley, who sits down for a two-part interview with Vice President-Elect Kamala Harris and her husband, Douglas Emhoff. Plus: John Dickerson looks at the challenges facing Joe Biden as he is sworn in as the 46th President; David Martin examines the security measures being taken for the inauguration; Jim Axelrod meets comedian Sarah Cooper, who found overnight success with her lip-sync videos of President Trump; Lee Cowan examines free speech on social media; Rita Braver reviews the second impeachment of Donald Trump; and Mo Rocca delves into the little-known story of Charles Curtis, the first Native American vice president.

Guest host: Mo Rocca. In our cover story, Susan Spencer meets a pioneer in the study of stroke recovery. Plus: David Pogue explains the GameStop stock battle pitting Wall Street hedge funds against day traders; Rocca talks with Mark Harris, author of a new biography of director Mike Nichols; Holly Williams profiles actor and Negroni-mixer Stanley Tucci; Tracy Smith talks with Andra Day and Lee Daniels, star and director of a new film about legendary jazz singer Billie Holiday; and Martha Teichner tells the story behind her new book, "When Harry Met Minnie," a true tale of puppy love and friendship.