In Kansas City, KS, Capt. John Cosgrove and his team of homicide detectives must track down a man suspected of beating his best friend to death with a cinder block--before he can flee the country; Dets. Greg Lawson and Mike York are hot on the trail of their murder suspect they know only as "Teeth.

In Dallas, a motorist passing along a highway discovers a man's body with a knife wound to the chest and his genitals burnt up; the shocking riddle of this scene propels the detectives on an odyssey through a rowdy world of Texas prostitutes and drugs.