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The MPU works to track down the kidnapped son of a doctor, but the case takes a turn when his mother gets in direct contact with the kidnapper. Meanwhile, Kemi expresses her concerns for Sidney's wellbeing to Nikki and Jason.
The MPU searches for a college student after she goes missing during a house party. Meanwhile, Sidney and Keith try to adjust to normal life again.
A foster care worker is reported as missing, but after he ends his own life, the MPU starts to investigate a pregnant woman he was seen with who has been missing for two years. Meanwhile, Sidney follows Keith and fears he may be dangerous.
A character-driven police procedural drama set in the Philadelphia Police Department's Missing Persons Unit (MPU). When police officer Nikki Batista's son goes missing, she joins the special unit to help other people find their loved ones, even as she searches for her own. "Alert: Missing Persons Unit" is a procedural drama with a heart-pounding, life-or-death search for a missing person in each episode, running alongside Nikki and her ex-husband's quest to find out the truth about their long-lost son. It's a case-of-the-week show with a case-of-a-lifetime story running through it -- a story that alternately brings the two main characters gut-wrenching heartache and heart-pounding joy.