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Jason and Nikki utilize a twin sister when a missing person case turns into a possible murder investigation. Meanwhile, Kemi helps C with his dating life and Keith gets reckless.
Jason and Mike search the Allegheny Mountains to find a missing couple. Meanwhile, Keith joins a trauma therapy group and bonds with another patient.
Sidney, upset that Jason and Nikki don't believe her claims about Keith, comes clean about the details surrounding the day of his disappearance, causing Jason to cast serious doubt on the boy claiming to be his son. Meanwhile, Mike's police mentor brings a missing officer's case to the MPU team.
A character-driven police procedural drama set in the Philadelphia Police Department's Missing Persons Unit (MPU). When police officer Nikki Batista's son goes missing, she joins the special unit to help other people find their loved ones, even as she searches for her own. "Alert: Missing Persons Unit" is a procedural drama with a heart-pounding, life-or-death search for a missing person in each episode, running alongside Nikki and her ex-husband's quest to find out the truth about their long-lost son. It's a case-of-the-week show with a case-of-a-lifetime story running through it -- a story that alternately brings the two main characters gut-wrenching heartache and heart-pounding joy.