The Sadlers have scraped and saved all their lives to have a home. When they finally move into one, the bank that has all their money closes and the previous owner of their home wants an immediate payoff. Not able to meet his demand they decide to take matters in their own hands.

An Indian warrior, Gregorio, is wounded escaping from the U.S. Army Fourth Cavalry, and the bigoted, ruthless Sgt. Emmet Holly sets out in hot pursuit. Gregorio encounters Kitty Russell, steals her horse and takes her hostage. Meanwhile, Marshal Matt Dillon is tracking all of them.