Eun Woo returns to her home on Heuksan Island to keep Se Poong safe. Upon hearing about her departure, Se Poong heads to the island himself. However, Kang Il ends up there as well. Physician Gye heads to Hanyang with Man Bok to settle Se Poong's problem. Meanwhile, Eun Woo is asked to attend to the wife of Interpreter Jung, who has encountered an unknown illness.

After Governor Ahn's failed attempt to harm Se Poong, he gets locked up in jail. Kang Il recovers from injuries and reports to the King what Governor Ahn did. Se Poong gets appointed as the head of the Medical Office and helps Eun Woo become a palace physician as well. Meanwhile, Granny prepares a gift for everyone before her long journey.