John aids investigators in pursuit of fugitive Pedro Espinoza, accused of two senseless murders in a two-year span. Later, after an 85-year-old woman is brutally stabbed to death, Cal joins the hunt for the alleged killer, Ervis Mecollari.

John Walsh joins the hunt for Adarus Black, who allegedly killed a young woman in broad daylight; Cal is in San Diego to help track down Michael Pratt, whose pornography ring allegedly ensnared over 100 women using fraud, coercion, and possibly force.