John is in pursuit of fugitive Jason Hines, accused of sexually abusing multiple minors and possibly involved in his wife's disappearance. Later, a slew of women allege they were sexually assaulted by chiropractor Steven Clifford on the run since 2002.

John's on the hunt for Jorge Rico-Ruvira, accused of murdering his girlfriend in 2020 and abducting their young son. Later, John and Cal shine a spotlight on the case of 15-year-old Sophie Reeder, who was abducted in 2017 and may be in grave danger.