On the night shift in Birmingham, paramedics are called to a man who's had a seizure. But they're warned that the patient has a history of being abusive towards ambulance crews.

In Kidderminster, paramedic Rob and technician Mike rush to a 21-month-old baby who has fallen unconscious. On the same shift in Coventry, two men collapse in a pub, leaving paramedics Neil Vann and Quoc Vo with a medical mystery to solve.