Frank Black a retired police consultant, who once worked for the FBI has just returned to his hometown with his wife and daughter. He decides to offer his support in a case and is given resources by a mysterious organization called the Millennium Group. Frank must catch the murderer with his ability to see out of the eyes of the killers. But this case draws him back into a world which he was trying to escape. But will Frank be able to save the latest victim in time before it is too late?

Against the initial resistance of the Group, Frank travels to Portland, Oregon, to investigate a murder at an animal shelter. He meets with Jim Horn, a profiler and candidate for the Millennium Group. But Horn is distracted by his imminent divorce, and there is tension between him and Frank. When the killer strikes again, Horn is losing control, and Frank not only has to catch the killer who leaves grisly messages on his victims, but he has to contend with Horn as well who is more than ready to stop the murderer with terminal prejudice.