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Emma and Frank investigate the mysterious biological research conducted by a former Millennium Group member who is dying from a mysterious disease.
A manhunt ensures when an escapee from a mental institution - who is believed to have decapitated two people - goes on the run with a deputy police officer. Leaving it is up to Frank and Emma to find the escapee. Meanwhile Emma's father grows ill.
When Frank receives a series of Polaroid photographs, showing his own death, Frank claims that someone is out to kill him, but authorities suspect he may be having a nervous breakdown...but is he?