Nicki and Mario must face the obstacle of male factor infertility as they try to start their family. Deaf couple Laura and Patrick navigate new challenges while pregnant during COVID. Ileana and Ross receive a diagnosis that changes their lives.

Maddie and Randal are forced to separate for the unforeseeable future due to Randal's failing grades. Dominique and Angelo receive test results that are critical to the success of their final transfer. Alicia is a determined to become a mother, even if it means doing it on her own.