During the following seven years, a new civilization rises and prospers under Simon's leadership. However, these peaceful times come to end when the threat mentioned in Lordgenome's last words starts to reveal itself.

Rossiu overthrows Simon and places him under arrest. But when the Anti-Spirals launch a large-scale attack on Kamina City, he is left with no choice but to let Simon fight the enemy using the Gurren-Lagann.