Extreme cleaning sisters Yvonne and Angela tackle a hoarder's house that is so bad the lady has been sleeping in the shed for the last six years; and father and son team Steve and Jamie have to rid a drugs den of thousands of dirty needles.

In Wales, extreme cleaning sisters Yvonne and Angela are called to a large house which was abandoned after its young owner had been struggling to cope. The whole place is littered with mouldy food and rubbish, there is an infestation of mice and things go from bad to worse when the water tank leaks, spreading water throughout the house. In Stevenage, mum and daughter cleaning team Maxine and Jasmine are tackling a house that was - until recently - home to 12 cats.