The four return from extinguishing a fire that Johnny started, with Ben and Sue upset with him. Johnny apologizes, saying that he'll do anything to make it up to them. Doctor Doom switches bodies with Reed by injecting him with something. With Reed stuck in Doom's body, he slowly escapes the confines of Doom's lair. The next day, Johnny wakes up and finds a camera crew in his room. Sue explains that, as payback for yesterday, Johnny must be followed around by 'A Day in the Life' so viewers can find out what a day in the life of the Fantastic Four is like. When Doom, as Reed, tells Sue to cancel his lectures, the three figure out something's up. Reed, as Doom, shows up at the Baxter Building and is greeted by the four. Believing him to be Doom, they trap him. Reed eventually convinces Sue to trust him and together they stop Doom from turning the Baxter Building into a weapon while also switching their bodies back.

Bruce Banner visits Reed at the Baxter Building. Banner changes into the Hulk and now the FF must stop his rampage in NYC and keep him from being captured by Agent Pratt who wants to use the Hulk for his own agenda. In the end, Pratt fails to stop Hulk and the Hulk is loose in the badlands. Otherwise, the Fantastic Four have saved the day again.