A lifetime of abuse and ridicule has left Michael anxious and afraid to leave the house. Now with the help of his devoted wife he must follow Dr. Now's programme to keep from eating himself to death.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.