Rio's feeling the heat from the FBI investigation, so he abruptly shuts down operations, cutting off Beth, Ruby, and Annie's money supply. Their attempt to go back to being ordinary housewives is short lived when Mary Pat puts the financial squeeze on them, forcing the three women to commit another heist.

Fearing for their lives, the ladies scramble to try to take down Rio. A kidney becomes available for Sara but Ruby and Stan don't have the money to pay for it. The three women hatch a plan that will solve both problems—one that involves returning to the scene of their first crime.